Triethylamine hydrochloride

Triethylamine hydrochloride

Triethylammonium chloride; Triethylamine monohydrochloride

CAS 554-68-7

Chemical Formula (C2H5)3N•HCl

Molecular Weight 137.65 g/mol

Triethylamine hydrochloride is a white, crystalline salt formed by the protonation of triethylamine with hydrochloric acid. It's a common ingredient in organic synthesis, often used as a base in reactions producing hydrogen chloride, which then reacts with triethylamine to form the salt. It's also used in ion-pair chromatography, as a raw material for pharmaceuticals and dyes, and as a catalyst. Due to its properties, it is also employed in reverse-phase HPLC for separating various substances. 
 

Industrial Uses

1. Performance Chemicals

  • Acid Neutralization: Triethylamine hydrochloride acts as a source of triethylamine, which can then neutralize acids formed during a reaction. For example, it's frequently used in the synthesis of esters and amides from acyl chlorides, where triethylamine hydrochloride is formed as a byproduct. 
  • Catalysis: It been used as a catalyst in certain reactions, such as the Friedel-Crafts reaction, to facilitate the formation of a desired product. 
  • pH Adjustment: In some cases, it is used to adjust the pH of a reaction mixture, particularly in situations where a slightly acidic or near-neutral pH is needed.
  • Semi-synthetic Antibiotic Side Chains: Triethylamine hydrochloride is also used in the synthetic manufacturing of semi-synthetic antibiotic side chains.

2. Pharmaceuticals

  • Base and catalyst: Triethylamine hydrochloride acts as a base and catalyst in various organic transformations, including acylation, alkylation, and condensation reactions. It facilitates nucleophilic substitutions, which are crucial in the synthesis of many pharmaceutical compounds.
  • Protein Purification: Triethylamine hydrochloride is used as a competing base in protein purification processes, helping to separate acidic, basic, and neutral drugs. It's also used in reverse-phase liquid chromatography for separating proteins and other biomolecules.

3. Polymers & Resins

  • Byproduct in Synthesis: TEA•HCl is often a byproduct in the synthesis of carbonate monomers, making its catalytic properties useful in utilizing this readily available compound.

4. Agrochemicals

  • Reagent in Synthesis: Triethylamine hydrochloride is frequently used as a reagent in the synthesis of various agrochemicals, including herbicides, insecticides, and fungicides. 
  • Quaternary Ammonium Compounds: It plays a role in the production of quaternary ammonium compounds, which are often used as active ingredients or adjuvants in pesticide formulations.

5. Paints, Coatings & Adhesives

  • Neutralizing Agent: Triethylamine hydrochloride is used to neutralize acidic groups (like carboxyl groups) in anionic stabilized waterborne resins, which are commonly found in paints. This helps in creating stable and homogeneous paint formulations.
  • Catalyst: It acts as a catalyst in the curing of epoxy and polyurethane systems, which are crucial components in many paints and coatings.
  • Water-borne Polyurethane Dispersions: Triethylamine hydrochloride is used in the production of these dispersions, which are used in various coatings.


 

Specifications

ASSAY 98%
Appearance White to off-white crystalline powder
Odor Mild amine-like odor
Boiling Point Decomposes before boiling
Melting Point 261°C
Density 1.0 g/cm3
Solubility Highly soluble in water; soluble in alcohol
Viscosity Not applicable
Flash Point Not flammable

Hazard Symbols

Flammables
Corrosives
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Triethylamine hydrochloride in India?
The price of Triethylamine hydrochloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Triethylamine hydrochloride in India?
You can purchase Triethylamine hydrochloride from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Triethylamine hydrochloride? 
Our minimum order quantity (MOQ) for Triethylamine hydrochloride is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Triethylamine hydrochloride supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.