Theophylline anhydrous

Theophylline anhydrous

1,3-Dimethylxanthine; Anhydrous Theophylline; Theophylline Base; Dimethylxanthine

CAS 58-55-9

Chemical Formula C₇H₈N₄O₂

Molecular Weight 180.16 g/mol

Theophylline anhydrous is a bronchodilator belonging to the methylxanthine class, used primarily in the treatment of respiratory diseases such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). It works by relaxing smooth muscles of the bronchial airways and pulmonary blood vessels and has mild diuretic and cardiac stimulant properties. The anhydrous form ensures stability and higher potency in formulations compared to its hydrated counterpart.

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Industrial Uses

1. Pharmaceuticals

  • Bronchodilator in Respiratory Therapy: Used in tablet, capsule, and injectable formulations to manage asthma, bronchitis, and COPD. Relaxes bronchial smooth muscles and improves airflow in obstructive pulmonary conditions. Often prescribed for maintenance therapy in chronic respiratory patients.
  • Combination Drug Formulations: Combined with other agents like salbutamol, ephedrine, or antihistamines for synergistic respiratory relief. Used in sustained-release preparations for long-term management of respiratory distress. Included in pediatric formulations for acute bronchospasm control.
  • Cardiovascular and CNS Stimulant: Exhibits mild stimulant activity on the central nervous system and heart. Sometimes used off-label for apnea in premature infants due to respiratory stimulation effects. Helps enhance diaphragmatic contractility in patients with ventilatory insufficiency.

2. Animal Healthacre

  • Bronchodilator in Animals: Used in veterinary practice for treating bronchitis, asthma-like conditions, and respiratory infections in animals. Prescribed for horses, dogs, and cats to improve breathing and reduce airway inflammation. Often compounded in oral pastes, powders, or injectable veterinary medications.
  • Supportive Therapy in Equine Medicine: Improves oxygen delivery and respiratory endurance in racehorses. Used under regulation in performance animals during recovery or treatment phases. Enhances lung capacity in exercise-induced pulmonary hemorrhage (EIPH) conditions.

3. Performance Chemicals

  • Pharmacological Research Agent: Used in laboratory studies related to adenosine receptor antagonism and phosphodiesterase inhibition. Acts as a model compound for studying bronchodilation and smooth muscle relaxation. Assists in in-vitro and in-vivo experiments involving cardiac, CNS, and respiratory function.
  • Reference Standard in Analytical Testing: Used in HPLC and spectroscopic method validation for pharmaceutical assay procedures. Serves as a marker in drug release studies and dissolution profiling. Included in pharmacopoeial monographs for calibration and QC standards.

Specifications

Assay ≥ 99.0%
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable (decomposes)
Melting Point 270 – 274 °C
Density Not available
Solubility Slightly soluble in water; soluble in alkaline solutions
Viscosity Not applicable (solid form)
Flash Point Not applicable

Hazard Symbols

Acute Toxicity
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Theophylline anhydrous in India?
The price of Theophylline anhydrous can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Theophylline anhydrous in India?
You can purchase Theophylline anhydrous from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Theophylline anhydrous?
Our minimum order quantity (MOQ) for Theophylline anhydrous is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 200 kg.

4. How can I ensure the quality of Theophylline anhydrous supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.