tert-Butyl chloride

tert-Butyl chloride

2-Chloro-2-methylpropane; tert-Butylchloride; t-Butyl chloride; Trimethylmethyl chloride

CAS 507-20-0

Chemical Formula C₄H₉Cl

Molecular Weight 92.57 g/mol

tert-Butyl chloride is an organic compound used as an intermediate in the production of pharmaceuticals, agrochemicals, and polymers. It is also applied in organic synthesis for introducing tert-butyl groups into various chemical structures.

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Industrial Uses

1. Pharmaceuticals

  • Intermediate for Synthesis of Anticholinergics and Bronchodilators: Used in preparing quaternary ammonium compounds that act as anticholinergic agents or smooth muscle relaxants (e.g., ipratropium-type drugs).
  • Precursor for Tertiary Amines and API Fragments: The highly reactive tert-butyl moiety is introduced into drug molecules to increase lipophilicity and steric bulk, aiding in bioavailability and metabolic stability.
  • Scaffold for CNS Drug Candidates: Incorporated into structures aimed at crossing the blood-brain barrier, as its bulky tert-butyl group assists in membrane permeability.

2. Agrochemicals

  • Intermediate for Pesticides and Herbicides: Serves as a precursor for tert-butyl substituted aromatic compounds, which act as selective herbicides or insect repellents.
  • Base for Volatile Agrochemical Compounds: Used in synthesizing volatile or gas-phase fumigants due to its low boiling point and high reactivity.

3. Performance Chemicals

  • Alkylating Agent: Acts as a strong electrophile for introducing tert-butyl groups via SN1 reactions with alcohols, phenols, and amines.
  • Precursor to tert-Butyl Alcohol: Hydrolyzed to tert-butanol, a key solvent and intermediate in producing ethers, flavors, and perfumes.
  • Base Compound for Grignard Reagent Formation: Although less common due to instability, it can be used in specialized organometallic synthesis.

4. Polymers & Resins

  • Monomer Modifier in Polymerization: Introduced into monomers to create branched or bulky polymer chains, affecting thermal stability and solubility.
  • Starting Material for tert-Butylated Polymers: Leads to tert-butyl acrylates or methacrylates, used in adhesives, coatings, and sealants.

5. Paints, Coatings & Adhesives

  • Intermediate in Synthesis of tert-Butyl Acrylates: Used in coatings formulations that require UV resistance, hydrophobicity, and durability.
  • Curing Agent in Epoxy Systems:  Can be used as a reactive diluent or modifying agent in epoxy and urethane coatings, offering faster curing times.

Specifications

Assay ≥ 99%
Appearance Colorless liquid
Odor Pungent, sweet, chloroform-like
Boiling Point 51–52 °C
Melting Point −26.5 °C
Density 0.84 g/cm³ at 20 °C
Solubility Insoluble in water; soluble in organic solvents
Viscosity ~0.4 cP at 20 °C
Flash Point −18 °C (closed cup)

Hazard Symbols

Flammables
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of tert-Butyl chloride in India?
The price of tert-Butyl chloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.630 100 6301 directly for a customized quote tailored to your needs.

2. Where can I buy tert-Butyl chloride in India?
You can purchase tert-Butyl chloride from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for tert-Butyl chloride?
Our minimum order quantity (MOQ) for tert-Butyl chloride is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of tert-Butyl chloride supplied by Multichem?              
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.