Tacrolimus IP

Tacrolimus IP

FK-506; Fujimycin; Prograf; Tacrolimus Monohydrate; Tacrolimus Anhydrous

CAS 104987-11-3

Tacrolimus IP is an immunosuppressive drug primarily used to prevent organ rejection in transplant recipients. It works by inhibiting calcineurin, thereby suppressing the activation of T-cells involved in immune responses. Due to its potent activity, Tacrolimus is widely used in formulations for kidney, liver, and heart transplant patients and is also applied topically in dermatological treatments for atopic dermatitis and other inflammatory skin disorders.

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Industrial Uses

1. Pharmaceuticals

  • Organ Transplantation Therapy: Used as an active pharmaceutical ingredient (API) in oral and injectable formulations for preventing organ rejection. Commonly prescribed after kidney, liver, and heart transplants. Works by inhibiting T-lymphocyte activation, reducing immune response against the graft.
  • Topical Dermatology: Formulated into ointments or creams for treating atopic dermatitis and eczema. Acts as a non-steroidal immunomodulator for long-term management of inflammatory skin conditions. Offers targeted relief without causing skin thinning, unlike corticosteroids.
  • Autoimmune Disorders: Investigated and used off-label for autoimmune conditions such as lupus, rheumatoid arthritis, and myasthenia gravis. Helps suppress overactive immune responses in severe immune-mediated diseases. Used in cases where conventional immunosuppressants are ineffective or poorly tolerated.
  • Ophthalmic Applications: Used in compounded formulations for treating severe dry eye and ocular surface inflammation. Applied in refractory cases of allergic conjunctivitis and keratoconjunctivitis. Provides localized immunosuppression for sensitive eye tissues.

Specifications

Assay ≥ 98.0%
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable (decomposes)
Melting Point 115 – 125 °C
Density Not available
Solubility Freely soluble in water and methanol
Viscosity Not applicable (solid form)
Flash Point Not applicable

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Tacrolimus IP in India?
The price of Tacrolimus IP can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Tacrolimus IP in India?
You can purchase Tacrolimus IP from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Tacrolimus IP?
Our minimum order quantity (MOQ) for Tacrolimus IP is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 200 kg.

4. How can I ensure the quality of Tacrolimus IP supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.