Sulfasalazine

Sulfasalazine

Azopyrin; Azopyrine; Azulfidine; Salazopyrin; Salazosulfapyridine

CAS 599-79-1

Chemical Formula C₁₈H₁₄N₄O₅S

Molecular Weight 398.89 g/mol

Sulfasalazine is used to treat ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) and also to maintain improvement of ulcerative colitis symptoms.

Industrial Uses

1. Pharmaceuticals

  • Treatment of ulcerative colitis: Sulfasalazine is indicated for the treatment of chronic inflammatory diseases such as rheumatoid arthritis in children and adults and ulcerative colitis. It also has off-label uses in treating patients with ankylosing spondylitis, mild to moderately active Crohn disease, psoriasis, and psoriatic arthritis.

2. Performance Chemicals

  • Sulfapyridine Synthesis: Sulfapyridine, a key component of sulfasalazine, is itself a sulfonamide drug. Its synthesis involves reacting 4-acetylaminobenzenesulfonyl chloride with 2-amino-4-methylpyrimidine. 
  • Azo Coupling: Sulfasalazine is synthesized by reacting sulfapyridine with salicylic acid through an azo coupling reaction. This reaction involves converting sulfapyridine into a diazonium salt and then coupling it with salicylic acid in an alkaline medium.

Specifications

Assay 98%
Appearance Yellow to orange-yellow crystalline powder
Odor Odorless or very faint medicinal odor
Boiling Point Decomposes before boiling
Melting Point 250°C
Density 1.6 g/cm3
Solubility Practically insoluble in water; soluble in dilute alkali and slightly soluble in ethanol
Viscosity Not applicable
Flash Point Not applicable

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Sulfasalazine in India?
The price of Sulfasalazine can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Sulfasalazine in India?
You can purchase Sulfasalazine from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Sulfasalazine? 
Our minimum order quantity (MOQ) for Sulfasalazine is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Sulfasalazine supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.