Secondary butyl chloride

Secondary butyl chloride

sec-Butyl chloride; 2-Chlorobutane; Butane, 2-chloro-; s-Butyl chloride

CAS 78-86-4

Chemical Formula C₄H₉Cl

Molecular Weight 92.57 g/mol

Secondary butyl chloride is an organic intermediate used in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is commonly utilized in alkylation reactions and other organic transformations in industrial and laboratory settings.

Industrial Uses

1. Pharmaceuticals

  • Intermediate in API Synthesis: Used to alkylate amines, thiols, or phenols in the production of pharmaceutical intermediates, especially where steric hindrance from the secondary position is needed for selectivity.
  • Precursor to Chiral Drug Compounds: Because it exists in optical isomers, it can be used in stereoselective synthesis, forming part of chiral centers in active pharmaceutical ingredients (APIs).
  • Useful in CNS Drug Building Blocks: Incorporated in molecules targeting the central nervous system, where sec-butyl groups improve membrane permeability.

2. Agrochemicals

  • Building Block for Insecticides and Herbicides: Used as an alkylating intermediate in the synthesis of selective agrochemicals with branched-chain moieties that mimic natural molecules.
  • Precursor for Bioactive Chlorinated Compounds: Plays a role in creating halogenated structures effective against fungi, bacteria, or weeds due to its reactivity and lipophilicity.

3. Performance Chemicals

  • Alkylating Agent: sec-Butyl chloride is commonly used in nucleophilic substitution reactions (SN1/SN2) to form ethers, esters, or amines for various fine chemical products.
  • Precursor to sec-Butyl Alcohol: Via hydrolysis, it converts to sec-butanol, a solvent and intermediate in plasticizers, coatings, and perfumes.
  • Intermediate in Grignard Reactions: Can be used to prepare sec-butyl Grignard reagents, which are valuable in organometallic chemistry and C–C bond formation.

4. Polymers & Resins

  • Modifier in Polymer Synthesis: Introduces branched side chains into polymer backbones to adjust flexibility, melting point, and chemical resistance.
  • Chain Transfer Agent: Used in controlled radical polymerizations to manage molecular weight and polymer structure.

5. Paints, Coatings & Adhesives

  • Intermediate for Acrylic Monomers: Converts to sec-butyl acrylate/methacrylate, which are used in UV-curable coatings, adhesives, and sealants for automotive and industrial applications.
  • Component in Solvent Blends: Its alcohol derivative (sec-butanol) is used as a solvent in coatings due to moderate evaporation and compatibility with resins.

6. Flavour & Fragrances

  • Precursor to sec-Butyl Esters: Used to make sec-butyl acetate, sec-butyl butyrate, etc., which impart fruity and solventy aromas to perfumes and food flavoring formulations.
  • Intermediate in Aroma Chemicals: sec-Butyl moiety is part of synthetic musk compounds and fragrance carriers.

Specifications

Assay ≥ 98%
Appearance Colorless liquid
Odor Sweet, chloroform-like
Boiling Point 68–69 °C
Melting Point −123 °C
Density 0.873 g/cm³ at 20 °C
Solubility Slightly soluble in water; soluble in organic solvents
Viscosity ~0.45 cP at 20 °C
Flash Point −8 °C (closed cup)

Hazard Symbols

Flammables
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Secondary butyl chloride in India?
The price of Secondary butyl chloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.630 100 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Secondary butyl chloride in India?
You can purchase Secondary butyl chloride from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Secondary butyl chloride?
Our minimum order quantity (MOQ) for Secondary butyl chloride is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Secondary butyl chloride supplied by Multichem?                   
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.