Secondary butyl bromide

Secondary butyl bromide

sec-Butyl bromide; 2-Bromobutane; Butane, 2-bromo-; s-Butyl bromide

CAS 78-76-2

Chemical Formula C₄H₉Br

Molecular Weight 137.02 g/mol

Secondary butyl bromide is an organic compound used as an intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is also employed in organic synthesis for alkylation and substitution reactions.

Industrial Uses

1. Pharmaceuticals

  • Intermediate in Drug Synthesis: sec-Butyl bromide is used as an alkylating agent for the synthesis of drug intermediates where a branched alkyl group is needed to influence lipophilicity and metabolic behavior.
  • Precursor to Chiral Compounds: Being a chiral secondary halide, it serves as a starting material for making enantiomerically enriched compounds, which are critical in the development of stereospecific drugs.

2. Agrochemicals 

  • Precursor for Branched Pesticide Molecules: Used in the synthesis of branched-chain insecticides and herbicides, where it contributes to improved fat solubility and cell membrane penetration, increasing efficacy against pests.
  • Intermediate in Surfactant-Type Formulations: Forms part of quaternary ammonium salts and nonionic surfactants, which are applied in agricultural formulations for better spreading and wetting properties.

3. Performance Chemicals 

  • Alkylating Reagent for Ethers, Esters & Amines: sec-Butyl bromide is commonly used in nucleophilic substitution reactions, where it alkylates nucleophiles such as alcohols, thiols, and amines, producing fine chemicals, custom additives, and intermediates.
  • Grignard Reagent Precursor (sec-Butylmagnesium bromide): Serves as a source for organomagnesium compounds, used to form carbon–carbon bonds in advanced organic synthesis.
  • SN1 vs. SN2 Reaction Substrate: sec-Butyl bromide is a benchmark molecule in academic and industrial labs for studying reaction mechanisms, particularly SN1/SN2 competition and rearrangement reactions.
  • Used in Mechanistic and Kinetic Studies: Due to its secondary nature and moderate steric hindrance, it is ideal for teaching organic chemistry concepts and conducting kinetic evaluations.

4. Polymer & Resins

  • Functional Monomer Component: In some specialty polymer applications, it can be used to introduce secondary butyl side groups, which modify flexibility, branching, and surface energy of polymers.
  • Intermediate for Surface-Treated Additives: Contributes to the synthesis of surface-active agents that improve coating properties or compatibility with hydrophobic materials.

Specifications

Assay ≥ 98%
Appearance Colorless liquid
Odor Sweet, ether-like
Boiling Point ~91 °C
Melting Point ~−123 °C
Density ~1.272 g/cm³ at 20 °C
Solubility Insoluble in water; soluble in alcohol, ether
Viscosity ~0.58 cP at 25 °C
Flash Point ~2 °C (closed cup)

Hazard Symbols

Flammables

FAQs

1. What is the current price of Secondary butyl bromide in India?
The price Secondary butyl bromide can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.630 100 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Secondary butyl bromide in India?
You can purchase Secondary butyl bromide from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Secondary butyl bromide?
Our minimum order quantity (MOQ) Secondary butyl bromide is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Secondary butyl bromide supplied by Multichem?                   
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.