Propyltriphenylphosphonium bromide

Propyltriphenylphosphonium bromide

Triphenyl(propyl)phosphonium bromide; Propyltriphenylphosphonium Bromide

CAS 6228-47-3

Chemical Formula C21H22BrP

Molecular Weight 373.31 g/mol

Propyltriphenylphosphonium bromide is an organic salt with the formula C21H22BrP. It consists of a propyl group attached to a triphenylphosphonium cation, and it's a colorless solid that is soluble in organic solvents like chloroform and dichloromethane. This compound is commonly used in organic synthesis, particularly in Wittig reactions and related transformations due to the reactivity of the phosphonium salt. It is also known for its use in the synthesis of various other organic compounds, including spirocyclic GPR119 agonists and cyclic acetal intermediates of azadirachtin. 

Industrial Uses

1. Performance Chemicals

  • Wittig Reaction: The propyl triphenyl phosphonium bromide is deprotonated by a strong base, forming a phosphorus ylide. This ylide then reacts with a ketone or aldehyde to form a new carbon-carbon double bond (alkene), effectively converting a carbonyl group into an alkene. 
  • Catalysis: Phosphonium salts like propyl triphenyl phosphonium bromide can act as catalysts or cocatalysts in various reactions, such as polymerization and cross-coupling reactions. 
  • Material Science: These compounds are also utilized in the synthesis of materials with specific properties, like ionic liquids and polymers, due to their unique structure and reactivity.

2. Pharmaceuticals

  • Drug Delivery: Its ability to target specific cellular locations, like mitochondria, makes it useful in developing drug delivery systems for enhanced therapeutic effects.

Specifications

Assay 98%
Appearance White to off-white crystalline powder
Odor Odorless or faint organic odor
Boiling Point Decomposes before boiling
Melting Point 235°C
Density 1.3 g/cm3
Solubility Soluble in polar solvents like water, methanol, ethanol, and DMSO
Viscosity Not applicable
Flash Point Not applicable

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Propyltriphenylphosphonium bromide in India?
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2. Where can I buy Propyltriphenylphosphonium bromide in India?
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3. What is the minimum order quantity (MOQ) for Propyltriphenylphosphonium bromide? 
Our minimum order quantity (MOQ) for Propyltriphenylphosphonium bromide is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Propyltriphenylphosphonium bromide supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.