Phenylephrine hydrochloride

Phenylephrine hydrochloride

Phenylephrine HCl; (R)-(−)-Phenylephrine hydrochloride

CAS 61-76-7

Chemical Formula C9H14ClNO2

Molecular Weight 203.62 g/mol

Phenylephrine Hydrochloride is the hydrochloride salt form of phenylephrine, a direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property.

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Industrial Uses

1. Pharmaceuticals

  • Nasal decongestion: Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery.

2. Animal Healthcare

  • Pupil Dilation: Phenylephrine HCl, commonly known as Ak-Dilate® or Ak-Nephrin®, is an agent used to dilate the pupil in dogs and cats. Pupil dilation is performed during some portions of an eye examination. Phenylephrine may also be used with other drugs such as atropine, to dilate the pupil prior to certain eye surgeries.

3. Performance Chemicals

  • Chiral Synthesis: Phenylephrine hydrochloride is often used as a starting material or an intermediate in the synthesis of other chiral compounds, especially those with similar structural motifs like other phenylethylamines. This is due to its readily available optically active form, (R)-(-)-Phenylephrine, which is a potent adrenergic agent. 
  • Key Intermediate: A common synthetic route involves the reduction of α-chloro 3-hydroxyacetophenone to form chiral 1-(3-hydroxyphenyl)-2-haloethanol, which is a crucial step in the synthesis of phenylephrine. This step is often followed by further reactions to introduce the desired substituents and ultimately form phenylephrine hydrochloride.

Specifications

Assay 98%
Appearance White or practically white, crystalline powder
Odor Odorless
Boiling Point Not applicable
Melting Point 143°C
Density 1.2 g/cm3
Solubility Freely soluble in water; slightly soluble in ethanol; practically insoluble in chloroform
Viscosity Not applicable
Flash Point Not applicable

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Phenylephrine hydrochloride in India?
The price of Phenylephrine hydrochloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Phenylephrine hydrochloride in India?
You can purchase Phenylephrine hydrochloride from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Phenylephrine hydrochloride? 
Our minimum order quantity (MOQ) for Phenylephrine hydrochloride is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Phenylephrine hydrochloride supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.