p-Bromo phenol

p-Bromo phenol

4-Bromophenol; Para-Bromophenol; p-Bromohydroxybenzene; 4-Hydroxybromobenzene

CAS 106-41-2

Chemical Formula C₆H₅BrO

Molecular Weight 173.01 g/mol

p-Bromo phenol is an organic intermediate widely used in the synthesis of pharmaceuticals, dyes, and fine chemicals. It is also utilized in research and industrial applications involving brominated aromatic compounds.

Industrial Uses

1. Pharmaceuticals

  • Intermediate in API Synthesis: p-Bromo phenol is used to build halogenated phenolic intermediates in various drug molecules, including analgesics, antipyretics, and CNS agents.
  • Precursor for Benzoxazoles and Phenyl Ethers: Used to synthesize heterocyclic scaffolds found in drugs via cyclization or etherification, where the phenol group aids in ring closure and the bromo group allows substitution.
  • Metabolism Modulator in Drug Design: The para-bromo group can help modify metabolic stability and receptor binding of aromatic rings in drug candidates.

2. Agrochemicals

  • Building Block for Halogenated Herbicides: p-Bromo phenol is incorporated into halogenated phenyl structures found in various herbicides and pesticides, where the bromo enhances lipophilicity and potency.
  • Intermediate for Fungicidal Compounds: Used in designing phenol-based fungicides, especially where the hydroxyl group plays a role in metal ion interaction or enzyme binding.
  • Synthesis of Plant Growth Regulators: Acts as a core aromatic unit for synthesizing regulatory molecules that mimic or inhibit plant hormones.

3. Fabric Solutions

  • Improves Dye Affinity and Fastness: The para-positioned Br group contributes to dye–substrate interactions and enhances resistance to fading.
  • Reactive Dye Base: Used to produce reactive or metal-complex dyes where hydroxyl groups enable binding to fibers like cotton or wool.

4. Polymers & Resins

  • Resin Crosslinker or Modifier: Acts as a functional additive in epoxy, phenolic, or acrylic resins to increase rigidity, chemical resistance, or introduce halogen functionality for flame resistance.
  • Monomer Synthesis for Specialty Polymers: The compound can be derivatized into brominated monomers used in UV-curable or heat-resistant polymer systems.
  • UV-Resistant Coating Additive: Incorporated into coatings to increase UV-blocking ability, protecting surfaces from degradation.

5. Performance Chemicals

  • Coupling Reaction Substrate: The bromo group is reactive in Suzuki, Heck, and Buchwald-Hartwig coupling reactions, enabling construction of biaryl or heteroaryl compounds.
  • Precursor for Custom Aromatic Derivatives: Used to synthesize functionalized phenols, ethers, and esters, including those used in cosmetics, lubricants, and surfactants.
  • Ligand Synthesis: Serves as a backbone for ligands or chelating agents in metal-catalyzed transformations or coordination compounds.

Specifications

Assay ≥ 98%
Appearance White to off-white crystalline solid
Odor Phenolic odor
Boiling Point ~238 °C
Melting Point 63–65 °C
Density ~1.8 g/cm³ at 25 °C
Solubility Slightly soluble in water; soluble in alcohol and ether
Viscosity Not applicable (solid at room temperature)
Flash Point 107 °C (closed cup, approximate)

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of p-Bromo phenol in India?
The price of p-Bromo phenol can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.630 100 6301 directly for a customized quote tailored to your needs.

2. Where can I buy p-Bromo phenol in India?
You can purchase p-Bromo phenol from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for p-Bromo phenol?
Our minimum order quantity (MOQ) for  p-Bromo phenol is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of p-Bromo phenol supplied by Multichem?                   
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.