Para toluene sulfonyl chloride

Para toluene sulfonyl chloride

p-Toluenesulfonyl chloride; 4-Methylbenzenesulfonyl chloride; Tosyl chloride; p-TsCl

CAS 98-59-9

Chemical Formula C₇H₇ClO₂S

Molecular Weight 190.65 g/mol

Para toluene sulfonyl chloride is an organic intermediate widely used in pharmaceuticals, agrochemicals, and dye manufacturing. It acts as a reagent in Performance Chemicals, particularly for introducing the tosyl group in organic reactions.

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Industrial Uses

1. Pharmaceuticals

  • Tosylating Agent in Drug Synthesis: PTSC is used to convert alcohols into tosylates, making them better leaving groups in nucleophilic substitution reactions. This is vital for the preparation of key drug intermediates.
  • Protecting Group for Amines: Used to protect amine groups temporarily during multi-step pharmaceutical synthesis to prevent side reactions.
  • Intermediate in API Production: PTSC serves as an intermediate or derivatization agent in the synthesis of antibiotics, cardiovascular drugs, and other complex Active Pharmaceutical Ingredients (APIs).

2. Agrochemicals

  • Intermediate for Pesticide Synthesis: Acts as a sulfonating agent to introduce functional groups in the production of herbicides and insecticides, helping develop active molecules with improved efficacy.
  • Intermediate for Fungicide Derivatives: PTSC is used to synthesize sulfonamide-based fungicidal agents, enhancing solubility and stability in agrochemical formulations.

3. Fabric Solutions

  • Coupling Agent for Dye Intermediates: In dye synthesis, PTSC is used to introduce sulfonyl groups that enhance water solubility and binding to fibers, especially in azo dyes and reactive dyes.
  • Functionalization Agent: Modifies aromatic compounds in dye structures to improve stability, reactivity, or light fastness.

4. Polymers & Resins

  • Functionalization of Polymers: Used to introduce sulfonyl functional groups on polymer backbones for specialized applications like ion-exchange resins and conductive polymers.
  • Chain Transfer or Crosslinking Agent: Acts as a crosslinking intermediate in thermosetting resins or specialty copolymers to modify hardness, flexibility, or resistance properties.

5. Performance Chemicals

  • General Intermediate for Tosyl Compounds: PTSC is a versatile building block for a wide range of tosylated chemicals, including tosyl hydrazones, tosyl amides, and sulfonylureas.
  • Catalyst Component or Reaction Promoter: Used in various organic synthesis reactions to promote selective substitutions or rearrangements.

Specifications

Assay ≥ 98% (typical commercial grade)
Appearance White to off-white crystalline powder
Odor Slight pungent odor
Boiling Point 135–137 °C (at 3 mmHg, decomposes)
Melting Point 66–69 °C
Density 1.37 g/cm³ (at 25 °C)
Solubility Insoluble in water; soluble in alcohols, acetone, ether
Viscosity Not applicable (solid)
Flash Point 145 °C (closed cup)

Hazard Symbols

Corrosives
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Para toluene sulfonyl chloride in India?
The price  of Para toluene sulfonyl chloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Para toluene sulfonyl chloride in India?
You can purchase Para toluene sulfonyl chloride from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Para toluene sulfonyl chloride?
Our minimum order quantity (MOQ) for Para toluene sulfonyl chloride is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Para toluene sulfonyl chloride supplied by Multichem?                   
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.