N-Iodosuccinimide

N-Iodosuccinimide

1-Iodopyrrolidine-2,5-dione; N-Iodosuccinimide

CAS 516-12-1

Chemical Formula C4H4INO2

Molecular Weight 224.98 g/mol

N-Iodosuccinimide, also known as 1-Iodopyrrolidine-2,5-dione, is a widely used iodinating and oxidizing reagent in organic chemistry. With its high reactivity and selectivity, NIS is an essential intermediate for introducing iodine atoms into organic molecules. It plays a vital role in the synthesis of pharmaceuticals, agrochemicals, and specialty compounds, particularly where controlled iodination is required. Its stability compared to molecular iodine makes it a preferred reagent in laboratory and industrial applications.

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Industrial Uses

1. Pharmaceuticals

  • Iodination Reagent: Used for selective iodination of aromatic and heteroaromatic compounds in drug discovery and active pharmaceutical ingredient (API) synthesis.
  • Oxidizing Agent: Applied in oxidative transformations in medicinal chemistry, enabling functional group modifications.
  • Halogenation Intermediate: Essential in the preparation of organoiodine compounds used as drug precursors.
  • Fine Chemical Synthesis: Facilitates regioselective and stereoselective reactions in advanced pharmaceutical intermediates.

2. Agrochemicals

  • Intermediate for Bioactive Molecules: Used in the synthesis of iodinated intermediates in pesticides, herbicides, and fungicides.
  • Iodination in Agro R&D: Provides a controlled method for introducing iodine into agrochemical compounds, improving bioavailability and stability.
  • Specialty Precursors: Acts as a reagent for developing novel agrochemicals with enhanced efficacy.

3. Performance Chemicals

  • Organic Synthesis: Widely employed in iodination reactions to produce dyes, pigments, and other functional materials.
  • Research Applications: Essential reagent in academic and industrial labs for developing new iodinated compounds.
  • Material Science: Used in the synthesis of iodinated polymers and specialty coatings.

Specifications

Assay ≥ 98.0%
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable (decomposes before boiling)
Melting Point 190–200 °C (decomposes)
Density ~2.28 g/cm³
Solubility Slightly soluble in water; soluble in acetonitrile, dichloromethane, and other organic solvents
Viscosity Not applicable
Flash Point Not applicable (solid, decomposes on heating)

Hazard Symbols

Flammables
Acute Toxicity
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of N-Iodosuccinimide in India?
The price of N-Iodosuccinimide can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy N-Iodosuccinimide in India?
You can purchase N-Iodosuccinimide from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments to global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for N-Iodosuccinimide?
Our minimum order quantity (MOQ) for N-Iodosuccinimide is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 200 kg.

4. How can I ensure the quality of N-Iodosuccinimide supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.