Nikethamide BP

"Coramine; Nikethamideum; Diethylamide of Nicotinic Acid; Nicotinic Acid Diethylamide

CAS 59-26-7

Chemical Formula C₁₀H₁₄N₂O

Molecular Weight ≥ 98.0% (BP grade)

Nikethamide BP is a central nervous system (CNS) respiratory stimulant primarily used to counteract respiratory depression. It is a derivative of nicotinamide and is known for its ability to stimulate the medullary respiratory center, leading to increased respiration rate and depth. Compliant with British Pharmacopoeia (BP) standards, Nikethamide is formulated into injectable and oral preparations for medical use in emergency respiratory support and performance enhancement under controlled conditions.

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Industrial Uses

1. Pharmaceuticals

  • Respiratory Stimulant in Emergency Care: Used to treat acute respiratory depression caused by overdose, anesthesia, or trauma. It stimulates the respiratory center in the medulla oblongata, increasing breathing rate. Commonly administered in injectable form in emergency and revival kits.
  • Antidote Supportive Therapy: Included in supportive care for poisoning or drug-induced CNS depression. It helps restore normal breathing and consciousness when combined with other antidotes. Frequently used in hospital toxicology and first-aid settings.
  • Stimulant in Fatigue Management: Historically used to improve alertness, attention, and performance under extreme fatigue. Though use is now regulated, it has been applied in endurance and military scenarios. It improves respiratory efficiency and oxygen intake in controlled environments.

2. Animal Healthcare 

  • Revival Agent for Animals: Administered in veterinary practice to stimulate respiration in sedated or anesthetized animals. Used during recovery from surgery or labor to restore breathing functions. Especially useful for small animals and livestock in rural or field operations.
  • Emergency Breathing Aid for Neonates: Used for newborn animals showing weak respiratory function post-birth. Improves lung expansion and oxygen intake during early development. A critical tool in veterinary neonatal care kits for breeders and farms.

Specifications

Assay ≥ 98.0% (BP grade)
Appearance White or almost white crystalline powder
Odor Odorless
Boiling Point 208 °C (approx.)
Melting Point 126–130 °C
Density ~1.1 g/cm³
Solubility Soluble in water, alcohol, and chloroform
Viscosity Not applicable (solid)
Flash Point > 100 °C

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Nikethamide BP in India?
The price of Nikethamide BP can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Nikethamide BP in India?
You can purchase Nikethamide BP from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Nikethamide BP?
Our minimum order quantity (MOQ) for Nikethamide BP is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 1 kg to 25 kg.

4. How can I ensure the quality of Nikethamide BP supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.