Meftformin hydrochloride

Meftformin hydrochloride

Metformin hydrochloride; Dimethylbiguanide hydrochloride; Glucophage (brand name)

CAS 1115-70-4

Chemical Formula C₄H₁₁N₅•HCl

Molecular Weight 165.63 g/mol

Metformin HCl is an oral antihyperglycemic agent used as first-line treatment for type 2 diabetes. It works by reducing hepatic glucose production and improving insulin sensitivity, thereby lowering blood glucose levels. It is typically taken in tablet form, often with meals to reduce gastrointestinal side effects, and may be used alone or in combination with other antidiabetic medications.

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Industrial Uses

1. Pharmaceuticals

  • Antidiabetic Agent: Metformin HCl is a first-line oral medication used to treat Type 2 Diabetes Mellitus. It helps lower blood glucose levels by improving insulin sensitivity and reducing hepatic glucose production.
  • Polycystic Ovary Syndrome (PCOS): Used off-label in the treatment of PCOS to improve insulin resistance and regulate menstrual cycles.
  • Obesity & Metabolic Syndrome: Sometimes used off-label to manage weight and metabolic parameters in overweight individuals, particularly those with insulin resistance.
  • Cancer Adjunct (Investigational): Being studied for its potential role in cancer therapy, especially in reducing cancer risk in diabetic patients due to its effects on insulin and glucose metabolism.

2. Performance Chemicals

  • Active Pharmaceutical Ingredient (API): Metformin HCl is manufactured as an API used in various finished dosage forms like tablets, sustained-release tablets, and oral suspensions.
  • Salt Formation Base: It is the hydrochloride salt of metformin, selected for its stability, solubility, and suitability in oral solid dosage formulations.

Specifications

Assay 98.5% – 101.0% (as per IP/USP/BP)
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Decomposes before boiling
Melting Point ~224 °C (with decomposition)
Density ~1.2 g/cm³ (estimated)
Solubility Slightly soluble in alcohol; practically insoluble in acetone and ether
Viscosity Not applicable
Flash Point Non-flammable

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Metformin HCl in India?
The price of Metformin HCl can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Metformin HCl in India?
You can purchase Metformin HCl from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Metformin HCl?
Our minimum order quantity (MOQ) for Metformin HCl is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Metformin HCl supplied by Multichem ?                     
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.