Magnesium valproate

Magnesium valproate

Magnesium Dipropylacetate; Magnesium Valproate Salt; Valproic Acid Magnesium Salt; VPM; Magnesium 2-propylpentanoate

CAS 125446-58-4

Chemical Formula C₁₆H₂₈MgO₄

Molecular Weight 306.68 g/mol

Magnesium Valproate is a salt of valproic acid and magnesium, primarily used as an anticonvulsant and mood stabilizer in the pharmaceutical industry. It offers the therapeutic benefits of valproic acid with improved gastrointestinal tolerability and a lower incidence of sodium-related side effects. Magnesium Valproate is used in extended-release oral formulations for the treatment of epilepsy, bipolar disorder, and migraine prophylaxis.

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Industrial Uses

1. Pharmaceuticals

  • Antiepileptic Drug (AED): Used in the manufacturing of tablets and sustained-release capsules for managing generalized and partial seizures. Provides long-term control of seizure activity by enhancing GABA neurotransmission. Preferred in cases where sodium load needs to be minimized (e.g., cardiac or renal patients).
  • Bipolar Disorder Treatment: Acts as a mood stabilizer for treating acute manic episodes and preventing relapse in bipolar disorder. Offers improved tolerability over sodium valproate, especially for patients with hypertension or sodium retention issues. Provides consistent plasma levels in modified-release formulations.
  • Migraine Prophylaxis: Employed in chronic migraine prevention, particularly in patients with coexisting epilepsy or mood instability. Offers a more stable pharmacokinetic profile, reducing migraine frequency and intensity. Lower risk of sodium-related side effects improves patient compliance.

Specifications

Assay ≥ 98.0% (on anhydrous basis)
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable (decomposes)
Melting Point ~130 °C (decomposes)
Density Not available
Solubility Soluble in water; slightly soluble in ethanol
Viscosity Not applicable (solid form)
Flash Point Not applicable

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Magnesium valproate in India?
The price of Magnesium valproate can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Magnesium valproate in India?
You can purchase Magnesium valproate from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Magnesium valproate?
Our minimum order quantity (MOQ) for Magnesium valproate is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 200 kg.

4. How can I ensure the quality of Magnesium valproate supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.