Levofloxacin hemihydrate

Levofloxacin hemihydrate

Levofloxacin Hydrate; Dyquin; S-(-)-Levofloxacin

CAS 138199-71-0

Chemical Formula C₁₈H₂₀FN₃O₄ • 1/2H₂O

Molecular Weight 370.38 g/mol

Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin.It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer).Levofloxacin, along with other quinolones such as gatifloxacin and moxifloxacin, is a member of the third generation of fluoroquinolones, colloquially referred to as the "respiratory quinolones" due to improved activity against gram-positive bacteria commonly implicated in respiratory infections.

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Industrial Uses

1. Pharmaceuticals

  • Antibiotic: Levofloxacin is FDA-approved for the treatment of nosocomial pneumonia, community-acquired pneumonia, acute bacterial rhinosinusitis, acute bacterial exacerbation of chronic bronchitis, acute bacterial prostatitis, acute pyelonephritis, urinary tract infection, skin or skin structure infections, prophylaxis, and treatment of plaque due to Yersinia pestis, and to reduce the incidence of disease progression of inhalational anthrax.

2. Animal Healthcare

  • Common treatment for Urinary tract infections: It is commonly used in veterinary medicine to treat respiratory and urinary tract infections due to sensitive organisms, pelvic inflammatory disease, prostatitis, endocarditis, anthrax, tuberculosis, traveler's diarrhea, and plague.

3. Performance Chemicals

  • Synthesis of Levofloxacin: Levofloxacin hemihydrate is synthesized through a series of chemical reactions, often starting from precursors like 2,3,4,5-tetrafluoro benzoic acid.

Specifications

Assay 98.50%
Appearance Light yellow to yellowish-white crystalline powder
Odor Odorless
Boiling Point Decomposes before boiling
Melting Point 223°C
Density 1.6 g/cm3
Solubility Freely soluble in water; slightly soluble in methanol; practically insoluble in acetone
Viscosity Not applicable
Flash Point Not flammable

FAQs

1. What is the current price of Levofloxacin hemihydrate in India?
The price of Levofloxacin hemihydrate can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Levofloxacin hemihydrate in India?
You can purchase Levofloxacin hemihydrate from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Levofloxacin hemihydrate? 
Our minimum order quantity (MOQ) for Levofloxacin hemihydrate is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Levofloxacin hemihydrate supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.