Itopride hydrochloride

Itopride hydrochloride

N-[4-[2-(Dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide hydrochloride; Itopride HCl; Ganaton (brand name); Gastroprokinetic agent

CAS 122898-67-3

Chemical Formula C₂₀H₂₆ClN₃O₃

Molecular Weight 393.89 g/mol

Itopride hydrochloride is a prokinetic agent used to treat gastrointestinal disorders such as functional dyspepsia and gastroesophageal reflux. It works by enhancing stomach and intestinal motility and relieving symptoms like bloating, nausea, and abdominal discomfort. Itopride acts through dopamine D2 receptor antagonism and acetylcholinesterase inhibition, promoting gastric emptying without affecting gastric acid secretion.

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Industrial Uses

1. Pharmaceuticals

  • Prokinetic agent: Itopride hydrochloride enhances gastrointestinal motility by stimulating acetylcholine release and inhibiting dopamine D2 receptors, improving gastric emptying and intestinal movement. It is used to treat functional dyspepsia and other gastric motility disorders.
  • Antiemetic: By blocking dopamine receptors in the chemoreceptor trigger zone (CTZ), it helps reduce nausea and vomiting associated with delayed gastric emptying and gastrointestinal disturbances.
  • Functional dyspepsia management: Commonly prescribed to treat non-ulcer dyspepsia (indigestion without a visible lesion), helping relieve symptoms like bloating, early satiety, and postprandial fullness.
  • Adjunct in GERD and chronic gastritis: Used in combination therapy with proton pump inhibitors (PPIs) or H2 blockers to enhance symptom relief in gastroesophageal reflux disease (GERD) and chronic gastritis by improving motility.

2. Food & Healthcare Ingredients

  • Digestive support formulation: In some advanced formulations, Itopride is explored in combination with digestive enzymes or probiotics to offer therapeutic benefits in managing mild functional digestive disorders.

Specifications

Assay ≥ 98%
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not available (decomposes before boiling)
Melting Point 198–202 °C (with decomposition)
Density Not available
Solubility Freely soluble in water, methanol; slightly soluble in ethanol and acetone
Viscosity Not applicable (solid compound)
Flash Point Not applicable (non-volatile solid)

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Itopride hydrochloride in India?
The price of Itopride hydrochloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Itopride hydrochloride in India?
You can purchase Itopride hydrochloride from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Itopride hydrochloride?
Our minimum order quantity (MOQ) for Itopride hydrochloride is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Itopride hydrochloride supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.