Domperidone 30%

Domperidone 30%

5-Chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one; Domperidonum; Domperidona

CAS 57808-66-9

Chemical Formula C₂₂H₂₄ClN₅O₂

Molecular Weight 425.91 g/mol

Domperidone 30% is a pharmaceutical formulation containing 30% of the active ingredient Domperidone, typically used as an antiemetic and prokinetic agent. It helps relieve nausea, vomiting, bloating, and discomfort caused by delayed gastric emptying by enhancing gastrointestinal motility and blocking dopamine receptors in the gut. This concentration is commonly used in veterinary and human medicine in either liquid or suspension form.

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Industrial Uses

1. Pharmaceuticals

  • Prokinetic agent: Domperidone enhances gastrointestinal motility by stimulating movement in the upper digestive tract, helping to treat conditions like gastroparesis, bloating, and nausea associated with slow gastric emptying.
  • Antiemetic: Used to prevent or relieve nausea and vomiting from various causes, including medication side effects (like those from chemotherapy or Parkinson’s drugs), gastrointestinal disorders, or infections. It works by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) of the brain.
  • Adjunct to Parkinson's therapy: Often prescribed alongside Levodopa or other dopamine agonists to counteract nausea without affecting the efficacy of the primary Parkinson’s treatment, since it doesn’t cross the blood-brain barrier easily.
  • Formulation of oral suspensions and dispersible tablets: The 30% concentrated form is used in pharmaceutical manufacturing to prepare various dosage forms like oral suspensions, rapidly dispersing tablets, or syrups, especially suited for pediatric and geriatric use.

Specifications

Assay 30% w/w Domperidone (typically in aqueous or polymer dispersion)
Appearance White to off-white suspension or viscous liquid
Odor Practically odorless
Boiling Point Not applicable (as 30% dispersion)
Melting Point ~242–247 °C (pure Domperidone)
Density Approx. 1.05–1.15 g/cm³ (depends on dispersion base)
Solubility Slightly soluble in water (pure), better in acidic solutions or solvents in formulation
Viscosity Depends on formulation; can range from 100–1000 cP
Flash Point >100 °C (if aqueous or non-flammable base used)

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Domperidone 30% in India?
The price Domperidone 30% can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Domperidone 30% in India?
You can purchase Domperidone 30% from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Domperidone 30%?
Our minimum order quantity (MOQ) Domperidone 30% is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Domperidone 30% supplied by Multichem?                      
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.