Divalproex sodium

Divalproex sodium

Divalproex Sodium Salt; DVP; Divalproex; Divalproate Sodium; Sodium Valproate and Valproic Acid Complex

CAS 76584-70-8

Chemical Formula (C₈H₁₅NaO₂)•(C₈H₁₆O₂)

Molecular Weight 310.41 g/mol

Divalproex Sodium is a stable coordination compound of sodium valproate and valproic acid in a 1:1 molar ratio. It is an extended-release anticonvulsant widely used for the treatment of epilepsy, bipolar disorder, and migraine prophylaxis. Divalproex Sodium offers improved gastrointestinal tolerability and controlled release of active drug compared to conventional valproate formulations, making it suitable for chronic use.

Enquire Now Back

Industrial Uses

1. Pharmaceuticals

  • Epilepsy Management: Used as an API in oral tablet and capsule formulations for treating partial and generalized seizures. Offers broad-spectrum control for absence, myoclonic, and tonic-clonic seizures. Suitable for monotherapy or adjunct therapy in both pediatric and adult patients.
  • Bipolar Disorder Treatment: Approved as a mood stabilizer for managing acute manic or mixed episodes associated with bipolar disorder. Helps prevent mood swings and recurrence of manic episodes. Preferred for patients intolerant to lithium or those with rapid cycling.
  • Migraine Prophylaxis: Indicated for the prevention of migraine headaches in adult patients. Reduces frequency and severity of attacks when used as a long-term preventive agent. Offers CNS stabilization without sedative effects.
  • Extended-Release Formulations: Used in sustained-release tablets for once-daily dosing to enhance compliance. Reduces peak-trough fluctuations, leading to better tolerability and effectiveness. Minimizes gastrointestinal side effects compared to immediate-release valproate.

Specifications

Assay ≥ 98.0%
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable (decomposes)
Melting Point 150 – 155 °C (with decomposition)
Density Not available
Solubility Freely soluble in water; soluble in ethanol
Viscosity Not applicable (solid form)
Flash Point Not applicable

Hazard Symbols

Acute Toxicity
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Divalproex sodium in India?
The price of Divalproex sodium can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Divalproex sodium in India?
You can purchase Divalproex sodium from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Divalproex sodium?
Our minimum order quantity (MOQ) for Divalproex sodium is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 200 kg.

4. How can I ensure the quality of Divalproex sodium supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.