Diazoxide

Diazoxide

Proglycem; 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide; Hyperstat; Diazoxideum

CAS 364-98-7

Chemical Formula C₈H₇ClN₂O₂S

Molecular Weight 230.67 g/mol

Diazoxide is a benzothiadiazine derivative used primarily as a vasodilator and hyperglycemic agent. It functions by opening potassium channels, which relaxes smooth muscles and inhibits insulin release from pancreatic β-cells. Diazoxide is commonly prescribed in the treatment of hypertensive emergencies, hypoglycemia, and insulinoma. It also plays a role in research settings for studying insulin regulation and ion channel activity.

Industrial Uses

1. Pharmaceuticals

  • Treatment of Hypoglycemia: Used in the management of persistent hypoglycemia, especially due to insulin-secreting tumors (insulinomas) or congenital hyperinsulinism.
  • Antihypertensive Agent: Acts as a potent vasodilator in hypertensive crises by relaxing vascular smooth muscles and lowering blood pressure.
  • Insulin Secretion Inhibitor: Used in endocrine disorders to control insulin release through ATP-sensitive potassium channel modulation.

Specifications

Assay ≥ 98%
Appearance White to pale yellow crystalline powder
Odor Odorless
Boiling Point Not applicable
Melting Point 230–232 °C
Density Not available
Solubility Slightly soluble in water, soluble in DMSO and methanol
Viscosity Not applicable
Flash Point Not applicable

Hazard Symbols

Acute Toxicity
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Diazoxide in India?
The price of Diazoxide can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Diazoxide in India?
You can purchase Diazoxide from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Diazoxide?
Our minimum order quantity (MOQ) for Diazoxide is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250 kg.

4. How can I ensure the quality of Diazoxide supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.