Choline salicylate 50%

Choline salicylate 50%

2-Hydroxybenzoic acid choline salt; Choline 2-hydroxybenzoate; Choline salicylic acid salt; Choline salicylate solution (50%)

CAS 5907-38-0

Chemical Formula C₉H₁₃NO₄

Molecular Weight 199.20 g/mol (for pure Choline Salicylate)

Choline salicylate 50% Solution is a topical, water-soluble anti-inflammatory and analgesic agent primarily used for oral and dental care. It is a salicylate derivative combined with choline to enhance solubility and absorption.

Industrial Uses

1. Pharmaceuticals

  • Topical Anti-inflammatory and Analgesic Agent: Choline Salicylate reduces inflammation and pain by inhibiting cyclooxygenase (COX) enzymes, which decreases prostaglandin production—key mediators of inflammation and pain. This makes it effective for treating mouth ulcers, sore gums, and teething pain with localized action that minimizes systemic side effects.
  • Mucosal Pain Reliever: Because it is highly soluble and well-absorbed by mucous membranes, it provides rapid relief when applied to oral tissues, soothing irritation and discomfort directly at the site.
  • Absorption Enhancer: The choline ion increases water solubility and facilitates deeper tissue penetration of the salicylate, improving the speed and efficiency of drug action compared to non-salt forms of salicylic acid.
  • Formulation Stabilizer: In pharmaceutical gels and creams, it helps maintain the physical stability and homogeneity of the product, ensuring consistent dosing and performance throughout the product’s shelf life.

2. Personal Care 

  • Soothing Agent for Irritated Skin and Mucosa: Choline Salicylate’s anti-inflammatory properties help calm mild skin irritations and inflammations, such as those caused by insect bites, minor burns, or dry skin, making it useful in oral gels and skin creams.
  • Mild Analgesic: It provides gentle pain relief suitable for sensitive areas like the mouth and facial skin, where stronger analgesics may be too harsh.
  • Emollient Enhancer: It contributes to the texture and feel of creams and gels, making products smoother and more pleasant to apply, which improves consumer acceptance.

3. Animal Healthcare 

  • Local Pain and Inflammation Reducer: Choline Salicylate is used topically on animals to reduce localized pain and swelling in injuries or oral lesions, aiding comfort and mobility.
  • Healing Promoter: By controlling inflammation, it creates a better environment for tissue repair and wound healing.
  • Safe Analgesic Alternative: It offers an option for animals where systemic NSAIDs might be contraindicated or have undesirable side effects.
  • Formulation Aid: Improves solubility and stability of veterinary ointments and gels, ensuring effective delivery of the active ingredient.

4. Performance Chemicals

  • Water-Soluble Active Ingredient: The choline salt form dissolves readily in water, which simplifies the manufacturing of aqueous-based gels, creams, and rinses, allowing uniform distribution of the active compound.
  • Anti-inflammatory Functional Component: It acts as the main therapeutic agent in formulations aimed at reducing pain and inflammation in topical products.
  • Bioavailability Enhancer: The formulation benefits from improved bioavailability due to choline’s facilitation of active ingredient penetration through biological membranes.
  • Stabilizer for Emulsions: By contributing to the stability of oil-water emulsions, it helps prevent separation and degradation, extending product shelf life and maintaining efficacy.

Specifications

Assay 50% w/w Choline Salicylate (in aqueous solution)
Appearance Clear to pale yellow viscous liquid
Odor Mild, characteristic odor
Boiling Point ~100°C (due to water content; pure compound decomposes)
Melting Point Not applicable (liquid solution); pure form: ~75–80°C
Density ~1.15 – 1.20 g/cm³ (at 20°C)
Solubility Miscible with water
Viscosity Moderate to high (depending on temperature)
Flash Point >100°C (aqueous solution; not considered highly flammable)

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Choline Salicylate 50% in India?
The price of Choline Salicylate 50% can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Choline Salicylate 50% in India?
You can purchase Choline Salicylate 50% from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Choline Salicylate 50%?
Our minimum order quantity (MOQ) for Choline Salicylate 50% is designed to cat er to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Choline Salicylate 50% supplied by Multichem ?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.