Cetirizine dihydrochloride

Cetirizine dihydrochloride

Cetirizine HCl; Zyrtec (brand name); 2-[2-[4-(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride

CAS 83881-51-0

Chemical Formula C₂₁H₂₅ClN₂O₃•2HCl

Molecular Weight 461.82 g/mol

Cetirizine dihydrochloride (Cetirizine di HCl) is a second-generation antihistamine commonly used to relieve allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and itching of the nose or throat. It is effective in treating conditions like allergic rhinitis (hay fever), urticaria (hives), and other skin allergies. Cetirizine works by blocking the action of histamine, a substance in the body that causes allergic symptoms, without causing significant drowsiness compared to first-generation antihistamines.

Industrial Uses

1. Pharmaceuticals

  • Active Pharmaceutical Ingredient (API): Cetirizine dihydrochloride is widely used as an antihistamine for the treatment of allergic conditions such as rhinitis, urticaria, hay fever, and seasonal allergies.
  • Formulations: It is used in tablets, syrups, and orally disintegrating forms for adults and children.
  • Non-Sedating Antihistamine: Classified as a second-generation antihistamine, it provides allergy relief without significant drowsiness, making it suitable for daytime use.

Specifications

Assay ≥ 98.0%
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable (decomposes before boiling)
Melting Point 110 – 115 °C
Density Not readily available; estimated ~1.2 g/cm³
Solubility Freely soluble in water and methanol; practically insoluble in hexane
Viscosity Not applicable (solid)
Flash Point Not applicable (non-volatile solid; decomposes on heating)

FAQs

1. What is the current price of Cetirizine dihydrochloride in India?
The price of Cetirizine dihydrochloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Cetirizine dihydrochloride in India?
You can purchase Cetirizine dihydrochloride from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Cetirizine dihydrochloride?
Our minimum order quantity (MOQ) for Cetirizine dihydrochloride is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Cetirizine dihydrochloride supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.