Carbamazepine

Carbamazepine

CBZ; Tegretol (brand name); Carbamaze; 5H-Dibenz[b,f]azepine-5-carboxamide; Carbamazepinum

CAS 298-46-4

Chemical Formula C₁₅H₁₂N₂O

Molecular Weight 236.27 g/mol

Carbamazepine is an anticonvulsant and mood-stabilizing drug belonging to the dibenzazepine class. It is widely used for the treatment of epilepsy, trigeminal neuralgia, and bipolar disorder. As a sodium channel blocker, it helps reduce excessive neuronal firing in the central nervous system. Carbamazepine is available as an active pharmaceutical ingredient (API) in IP, BP, and USP grades for use in both immediate and extended-release dosage forms.

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Industrial Uses

1. Pharmaceuticals

  • Anticonvulsant Therapy: Used in tablets, chewable tablets, and extended-release formulations for the treatment of partial seizures and generalized tonic-clonic seizures. Provides effective long-term control of epilepsy by stabilizing hyperexcitable nerve membranes. Often prescribed as first-line therapy for focal epilepsies.
  • Neuropathic Pain Management: Approved for the treatment of trigeminal neuralgia and glossopharyngeal neuralgia. Reduces paroxysmal pain episodes by inhibiting nerve conduction in sensory neurons. Preferred agent for idiopathic or classic trigeminal pain syndromes.
  • Mood Stabilizer in Bipolar Disorder: Used as a second-line option for acute manic and mixed episodes in bipolar disorder. Helps prevent recurrence and stabilize mood over prolonged use. Often used in patients who do not respond well to lithium therapy.
  • Extended-Release Formulations: Employed in controlled-release tablets to maintain steady blood levels and reduce dosing frequency. Improves patient adherence and minimizes peak-related side effects. Suitable for chronic neurological and psychiatric use.

2. Animal Healthcare 

  • Seizure Management in Companion Animals: Investigated for use in controlling idiopathic epilepsy in dogs and cats. Administered under veterinary supervision when phenobarbital is ineffective or contraindicated. Requires careful therapeutic monitoring for hepatotoxicity.

Specifications

Assay ≥ 98.5%
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable (decomposes)
Melting Point 189 – 193 °C
Density Not available
Solubility Practically insoluble in water; soluble in acetone and methylene chloride
Viscosity Not applicable (solid form)
Flash Point Not applicable

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Carbamazepine in India?
The price of Carbamazepine can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Carbamazepine in India?
You can purchase Carbamazepine from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Carbamazepine?
Our minimum order quantity (MOQ) for Carbamazepine is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 200 kg.

4. How can I ensure the quality of Carbamazepine supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.