Bosentan monohydrate

Bosentan monohydrate

Tracleer Monohydrate; Bosentan hydrate; Ro 47-0203 Monohydrate; Bosentanum

CAS 179841-12-4

Chemical Formula C27H29N5O6S•H2O

Molecular Weight 569.63 g/mol

Bosentan Monohydrate is an endothelin receptor antagonist used primarily to manage pulmonary arterial hypertension (PAH). It improves exercise capacity and delays clinical worsening by relaxing blood vessels in the lungs. Bosentan blocks the action of endothelin-1, a substance in the body that causes blood vessels to constrict, thus helping to lower blood pressure in the lungs.

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Industrial Uses

1. Pharmaceuticals

  • Pulmonary Arterial Hypertension (PAH): Primarily used to treat PAH in patients to reduce symptoms like shortness of breath and improve physical activity tolerance.
  • Endothelin Receptor Blockade: Functions by inhibiting endothelin-1 receptors (ETA and ETB), which are responsible for blood vessel constriction.
  • Combination Therapy: Often used in conjunction with other PAH medications such as sildenafil or prostacyclins for synergistic therapeutic benefits.

Specifications

Assay ≥ 98%
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable
Melting Point ~120–125 °C
Density Not available
Solubility Practically insoluble in water, soluble in DMSO and ethanol
Viscosity Not applicable
Flash Point Not applicable

FAQs

1. What is the current price of Bosentan monohydrate in India?
The price of Bosentan monohydrate can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Bosentan monohydrate in India?
You can purchase Bosentan monohydrate from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Bosentan monohydrate?
Our minimum order quantity (MOQ) for Bosentan monohydrate is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250 kg.

4. How can I ensure the quality of Bosentan monohydrate supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.