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Atorvastatin calcium trihydrate USP

Atorvastatin Calcium USP; Lipitor Calcium Salt; Atorvastatin Calcium Hydrate; Calcium Salt of (3R,5R)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid trihydrate

CAS 134523-03-8

Chemical Formula C66H68CaF2N4O10•3H2O

Molecular Weight 1209.42 g/mol (including trihydrate and calcium)

Atorvastatin Calcium Trihydrate is the calcium salt form of atorvastatin, a widely prescribed statin used to manage cholesterol levels and reduce the risk of cardiovascular diseases. It works by inhibiting HMG-CoA reductase, the enzyme responsible for cholesterol synthesis in the liver. This results in reduced levels of LDL ("bad") cholesterol and triglycerides while increasing HDL ("good") cholesterol. As a USP-grade substance, it meets strict pharmaceutical standards for purity and efficacy.

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Industrial Uses

1. Pharmaceuticals

Cholesterol Reduction: Used to treat hypercholesterolemia and mixed dyslipidemia by lowering LDL cholesterol and triglyceride levels.
Cardiovascular Risk Prevention: Reduces the risk of heart attacks, strokes, and other cardiovascular events in high-risk patients, including those with diabetes or hypertension.
Familial Hypercholesterolemia: Prescribed for patients with inherited high cholesterol levels, including both heterozygous and homozygous familial hypercholesterolemia.
Adjunct Therapy: Often combined with dietary changes and lifestyle modifications for optimal lipid control.
Formulations: Available in various oral tablet strengths and used in combination products (e.g., with ezetimibe or amlodipine).

Specifications

Assay	≥ 98.0% (on dried basis, USP standard)
Appearance	White to off-white crystalline powder
Odor	Odorless
Boiling Point	Not applicable (decomposes)
Melting Point	159–160 °C (decomposes)
Density	Not available
Solubility	Practically insoluble in water, soluble in methanol and ethanol
Viscosity	Not applicable
Flash Point	Not applicable

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FAQs

1. What is the current price of Atorvastatin calcium trihydrate in India?
The price of Atorvastatin calcium trihydrate can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Atorvastatin calcium trihydrate in India?
You can purchase Atorvastatin calcium trihydrate from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Atorvastatin calcium trihydrate?
Our minimum order quantity (MOQ) for Atorvastatin calcium trihydrate is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250 kg.

4. How can I ensure the quality of Atorvastatin calcium trihydrate supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.