Amlodipine besylate

Amlodipine besylate

Norvasc; Amlodipine Benzene Sulfonate; 3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate; Besylate salt of Amlodipine

CAS 111470-99-6

Chemical Formula C26H31ClN2O8S

Molecular Weight 567.1 g/mol

Amlodipine besylate is a medication primarily used to treat high blood pressure (hypertension) and chest pain (angina). It belongs to a class of drugs called calcium channel blockers, which help relax and widen blood vessels, improving blood flow and reducing the heart’s workload. This helps lower blood pressure and prevent angina attacks, promoting better cardiovascular health.

Enquire Now Back

Industrial Uses

1. Pharmaceuticals

  • Antihypertensive: Blocks calcium channels in blood vessels, causing vasodilation and reducing blood pressure.
  • Anti-anginal: Improves oxygen supply to the heart muscle by dilating coronary arteries, reducing chest pain.
  • Combination therapy: Formulated with other APIs (like ACE inhibitors, beta-blockers) to provide multi-mechanism blood pressure control.
  • Extended-release formulations: Used in sustained-release tablets for once-daily dosing, improving patient compliance.
  • Generic drug production: Enables cost-effective alternatives to brand-name drugs.
  • API supplier: Companies manufacture and supply Amlodipine Besylate in bulk for pharmaceutical formulation.
  • Pharmacological studies: Used to study calcium channel blockers’ effects on vascular smooth muscle and cardiac tissues.
  • Formulation development: R&D of novel delivery systems (e.g., nanoparticles, transdermal patches).
  • Clinical trials: Testing new therapeutic indications or combination treatments.
  • Toxicological studies: Safety profiling during drug development.

2. Perfomance Chemicals

  • Synthesis: Production of Amlodipine base followed by conversion to Besylate salt for better stability and solubility.
  • Bulk production: Manufacturing large quantities for global pharmaceutical supply.
  • Process optimization: Enhancing yield, purity, and environmental sustainability in synthesis.

Specifications

Assay ≥98.0% (typically pharmaceutical grade)
Appearance White to off-white crystalline powder
Odor Odorless
Boiling Point Not applicable (decomposes before boiling)
Melting Point 199 – 201°C (with decomposition)
Density Not readily available (solid compound)
Solubility Freely soluble in methanol, sparingly soluble in water
Viscosity Not applicable (solid powder)
Flash Point Not applicable (non-volatile solid)

FAQs

1. What is the current price of Amlodipine besylate in India?
The price Amlodipine besylate can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy Amlodipine besylate in India?
You can purchase Amlodipine besylate from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Amlodipine Besylate?
Our minimum order quantity (MOQ) Amlodipine besylate is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Amlodipine besylate supplied by Multichem?                      
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.