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4-Fluorobenzoyl Chloride

p-Fluorobenzoyl chloride; 4-Fluorobenzoic acid chloride

CAS 403-43-0

Chemical Formula C7H4ClFO

Molecular Weight 158.56 g/mol

4-Fluorobenzoyl chloride is an acyl chloride with a fluorine substituent on the benzene ring, making it a versatile building block in organic synthesis. It is commonly used as an acylating agent, particularly in the introduction of fluorinated benzoyl groups in pharmaceuticals and agrochemicals. Its reactivity stems from the acyl chloride group, which readily participates in various chemical reactions like amidation and esterification.

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Industrial Uses

1. Pharmaceuticals

Acylating Agent: 4-Fluorobenzoyl chloride is a reactive compound due to its acyl chloride functional group. This allows it to easily react with other molecules, particularly alcohols and amines, to form esters and amides, respectively.
Donepezil: This drug, used to treat Alzheimer's disease, also incorporates a fluorinated benzoyl group synthesized using 4-fluorobenzoyl chloride.

2. Agrochemicals

Agrochemical Synthesis: This compound is used to create various active ingredients for crop protection products Agrochemical Synthesis:, including fungicides and herbicides. Example; Flumorph: The fungicide flumorph is synthesized using 4-fluorobenzoyl chloride as a key building block.

3. Polymers & Resins

Lower dielectric constants: Fluorine and rigid structures can reduce the material's ability to store electrical energy, making them suitable for high-frequency applications like microelectronics.
Improved thermal stability: The presence of strong carbon-fluorine bonds and rigid structures can enhance the material's resistance to heat.

4. Flavours & Fragrances

Intermediate: 4-Fluorobenzoyl chloride is primarily used in the flavors and fragrances industry as a building block for synthesizing various aromatic compounds.

Specifications

Assay	97%
Appearance	Colorless to pale yellow liquid`
Odor	Pungent, irritating odor typical of acyl chlorides
Boiling Point	213°C
Melting Point	Not defined
Density	1.36 g/cm3
Solubility	Reacts with water; soluble in organic solvents such as ether, toluene, DCM
Viscosity	Not determined
Flash Point	93°C

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FAQs

1. What is the current price of 4-Fluorobenzoyl chloride in India?
The price of 4-Fluorobenzoyl chloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy 4-Fluorobenzoyl chloride in India?
You can purchase 4-Fluorobenzoyl chloride from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for 4-Fluorobenzoyl chloride?
Our minimum order quantity (MOQ) for <chemical name> is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of 4-Fluorobenzoyl chloride supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.