4-Bromobenzyl bromide

4-Bromobenzyl bromide

p-Bromobenzyl bromide; 1-(Bromomethyl)-4-bromobenzene; 4-Bromophenylmethyl bromide; Para-bromobenzyl bromide

CAS 589-15-1

Chemical Formula C7H6Br2

Molecular Weight 249.93 g/mol

4-Bromobenzyl bromide is an organic intermediate used in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is often employed in alkylation reactions and for building complex aromatic structures in chemical synthesis.

Industrial Uses

1. Pharmaceuticals

  • Intermediate in Drug Synthesis: Used to prepare substituted aromatic compounds where both the benzyl and para-bromo groups can be further functionalized to create intermediates for antihistamines, anti-infectives, and cardiovascular agents.
  • Precursor for Quaternary Ammonium Salts: The benzylic bromide group is highly reactive, making it ideal for preparing quaternized nitrogen-containing drugs, such as antibacterial agents and muscle relaxants.
  • Scaffold for CNS and Anticancer Molecules: The dual bromine substitution supports molecular docking in enzyme inhibitors, particularly in receptor-targeted or DNA-binding drugs.

2. Agrochemicals

  • Building Block for Insecticides & Fungicides: Acts as a reactive intermediate to prepare halogenated benzyl derivatives with broad-spectrum pesticidal activity.
  • Used in Synthesis of Plant Growth Modifiers: Precursor for compounds designed to regulate flowering, germination, or stress resistance in crops.
  • Precursor for Herbicide Compounds: Supports development of aromatic ring-containing herbicides, often with high selectivity and environmental persistence.

3. Performance Chemicals

  • Bifunctional Intermediate: Contains two reactive sites: one for nucleophilic substitution and another for cross-coupling, making it suitable for multi-step synthesis of dyes, ligands, and catalysts.
  • Reactant in Grignard and Organometallic Chemistry: Useful in halogen-metal exchange reactions, especially in forming organobromine reagents.
  • Alkylating Agent for Synthesis of Specialty Chemicals: The bromomethyl group acts as a powerful electrophile for producing ether, amine, or thioether linkages in customized molecules.

4. Fabric Solutions

  • Precursor for Dye Coupling Reactions: Used to form aryl amines or benzyl ketones, which are key intermediates in azo and disperse dye production.
  • Reactive Dye Modifier: The para-bromo and benzylic bromide sites allow for easy substitution, enabling dye chemists to develop water-soluble and reactive colorants.

 5. Polymers & Resins

  • Crosslinking Agent: The benzylic bromide group allows it to be used in crosslinking reactions in polymer chemistry, particularly for creating network structures in resins and thermosets.
  • Precursor for Functional Polymers: Incorporated into side chains or end groups of polymers for specific reactivity (e.g., ion-exchange resins or electronic materials).

Specifications

Assay ≥ 98%
Appearance White to off-white crystalline solid
Odor Pungent, irritating odor
Boiling Point ~270 °C (decomposes)
Melting Point ~52–55 °C
Density ~1.87 g/cm³ at 25 °C
Solubility Insoluble in water; soluble in alcohol, acetone, ether
Viscosity Not applicable (solid at room temp)
Flash Point ~138 °C (closed cup)

Hazard Symbols

Flammables
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of 4-Bromobenzyl bromide in India?
The price 4-Bromobenzyl bromide can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.630 100 6301 directly for a customized quote tailored to your needs.

2. Where can I buy 4-Bromobenzyl bromide in India?
You can purchase 4-Bromobenzyl bromide from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for 4-Bromobenzyl bromide?
Our minimum order quantity (MOQ) 4-Bromobenzyl bromide is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of 4-Bromobenzyl bromide supplied by Multichem?                   
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.