4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one

4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one

4,4,4-Trifluoro-1-(p-tolyl)butan-1-one; 1-(4-Methylphenyl)-4,4,4-trifluorobutan-1-one; Trifluoromethyl aryl ketone; TFMB

CAS 1070-64-0

Chemical Formula C11H11F3O

Molecular Weight 216.20 g/mol

4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one is a specialty intermediate used primarily in pharmaceutical synthesis, agrochemicals, and fluorinated compound research. Its trifluoromethyl group offers high metabolic stability and lipophilicity, which makes it valuable in the design of bioactive molecules. It is a key building block in the development of anti-inflammatory, antiviral, and pesticidal agents.

Industrial Uses

1. Pharmaceuticals

  •  Drug Intermediate: Widely used as a fluorinated ketone intermediate in the synthesis of pharmaceuticals such as anti-inflammatory and     antiviral drugs.
  •  Fluorinated Scaffold: Offers metabolic resistance and improved binding properties in active pharmaceutical ingredients (APIs).
  •  Medicinal Chemistry Research: Used in structural optimization of drug candidates due to its unique trifluoromethyl group.

2. Agrochemicals

  •  Pesticide Synthesis: Used as a key intermediate in the development of fungicides, herbicides, and insecticides.
  •  Enhanced Bioavailability: The trifluoromethyl moiety improves membrane permeability and efficacy in crop protection chemicals.

3. Performance Chemicals

  •  Fluorochemical Intermediate: Used in synthesis of advanced fluorinated compounds for chemical and material science.
  •  Perfume & Fragrance Chemistry: Occasionally explored for its ketonic stability in fragrance intermediate design.

Specifications

Assay ≥ 98%
Appearance Clear to pale yellow liquid or crystalline solid
Odor Mild aromatic odor
Boiling Point ~225–230 °C
Melting Point 15–20 °C (varies with purity)
Density ~1.22 g/cm³ at 25 °C
Solubility Soluble in organic solvents (ethanol, acetone, DCM)
Viscosity Low to moderate (depending on form and temperature)
Flash Point ~100 °C (closed cup)

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of 4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one in India?
The price of 4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy 4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one in India?
You can purchase 4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for 4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one?
Our minimum order quantity (MOQ) for 4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250 kg.

4. How can I ensure the quality of 4,4,4-Trifluoro-1-(4-methylphenyl)butan-1-one supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.