3-Bromoanisole

3-Bromoanisole

m-Bromoanisole; 1-Bromo-3-methoxybenzene; 3-Methoxybromobenzene; Meta-bromoanisole

CAS 2398-37-0

Chemical Formula C7H7BrO

Molecular Weight 187.03 g/mol

3-Bromoanisole is an aromatic compound used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is valued in organic synthesis for introducing methoxy and bromo functional groups into complex molecules.

Industrial Uses

1. Pharmaceuticals

  • Intermediate for API Core Structures: Used to construct aromatic intermediates with selective substitution at meta-position, critical for drugs requiring controlled hydrophilicity and metabolism.
  • Precursor for CNS-Active Compounds: The methoxy group provides lipophilicity while the bromine enables further derivatization, supporting synthesis of sedatives, anxiolytics, and anti-epileptics.
  • Scaffold for Phenol/Aniline Derivatives: Demethylated to 3-bromophenol or aminated to 3-bromoaniline—both are versatile in synthesizing antibacterials and analgesics.

2. Agrochemicals

  • Intermediate for Brominated Herbicides: Used to develop halogenated benzene derivatives in pre- and post-emergence herbicides where selectivity and environmental degradation rate are tailored via substitution.
  • Building Block for Insecticides & Fungicides: The bromo and methoxy substitution allows for designing molecules with optimal lipophilicity and activity against plant pathogens or insects.
  • Starting Material for Regulatory Compounds: Converted to substituted benzoic acids and nitriles used in growth inhibitors and hormonal balance modifiers for crops.

3. Performance Chemicals

  • Core Unit for Cross-Coupling Synthesis: Participates in Suzuki, Sonogashira, and Heck reactions to yield biaryl compounds and conjugated systems used in optical brighteners and specialty additives.
  • Ether Cleavage & Derivative Synthesis: Methoxy group can be cleaved or substituted to produce aldehydes, esters, or acids required in fragrance, lubricant, or flavor chemistry.
  • Halogen-Metal Exchange for Custom Synthesis: The bromo group is used in halogen-lithium or halogen-magnesium exchange reactions to generate organometallic intermediates for further elaboration.

4. Polymers & Resins 

  • Functional Monomer Precursor: Converted into monomers that form UV-curable coatings, adhesives, or heat-resistant polymers.
  • Crosslinking and Side-Chain Modifier: Used to modify chain ends or pendant groups on polymer backbones to introduce thermal stability or halogen-based flame retardancy.
  • Photopolymer Resin Additive: Anisole derivatives improve solubility and flow behavior in photoinitiated resin systems for 3D printing or microelectronics.

5. Fabric Solutions

  • Dye Intermediate (Azo, Anthraquinone): Used to synthesize aromatic amines or hydroxyl derivatives that are then coupled to produce high-intensity dyes.
  • Color Shift and Solubility Modifier: Methoxy groups improve water and solvent solubility of dyes, while bromination modifies chromophore behavior for better textile performance.
  • Reactive Dye Precursor: Participates in substitution reactions to generate reactive groups that bind covalently to fabric fibers, especially in cotton and silk processing.

6.  Personal Care 

  • Intermediate for Fragrance Molecules: Forms methoxy-substituted benzoates or aldehydes that are core notes in perfumes.
  • UV-Stable Additive Synthesis: Used in the preparation of UV-absorbers or antioxidant agents for sunscreen and anti-aging products.

Specifications

Assay ≥ 98%
Appearance Colorless to pale yellow liquid
Odor Mild aromatic odor
Boiling Point ~216–218 °C
Melting Point Not applicable (liquid at room temperature)
Density ~1.50 g/cm³ at 25 °C
Solubility Insoluble in water; soluble in organic solvents (e.g. ether, benzene)
Viscosity Low viscosity
Flash Point ~95 °C (closed cup)

Hazard Symbols

Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of 3-Bromoanisole in India?
The price 3-Bromoanisole can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.630 100 6301 directly for a customized quote tailored to your needs.

2. Where can I buy 3-Bromoanisole in India?
You can purchase 3-Bromoanisole from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for 3-Bromoanisole?
Our minimum order quantity (MOQ) 3-Bromoanisole is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of 3-Bromoanisole supplied by Multichem?                   
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.