3,4-Difluoronitrobenzene

3,4-Difluoronitrobenzene

1,2-Difluoro-4-nitrobenzene; 1-Nitro-3,4-difluorobenzene

CAS 369-34-6

Chemical Formula C6H3F2NO2

Molecular Weight 159.09 g/mol

3,4-Difluoronitrobenzene (3,4-DFNB) is a chemical compound used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It features a benzene ring with two fluorine atoms and a nitro group, making it reactive in various chemical transformations like nucleophilic aromatic substitution. Its utility extends to the synthesis of biologically active molecules and effective pest control agents. 

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Industrial Uses

1. Pharmaceuticals

  • Key Intermediate: 3,4-Difluoronitrobenzene is a crucial starting material in the synthesis of many pharmaceutical compounds. 
  • Oxazolidinone Antibiotics: It's a key component in the synthesis of oxazolidinone antibiotics like linezolid. These antibiotics are effective against Gram-positive bacteria and are particularly important in treating infections caused by multidrug-resistant strains.

2. Agrochemicals

  • Intermediate in Synthesis: 3,4-Difluoronitrobenzene is a versatile chemical compound used as a starting material for synthesizing a wide range of agrochemicals.

3. Performance Chemicals

  • Organic Synthesis: Researchers utilize 3,4-DFNB's reactivity in the construction of more complex organic molecules. It undergoes reactions like nucleophilic aromatic substitution with amines and thiols, and the nitro group can be reduced to an amine.

Specifications

Assay 98%
Appearance Pale yellow to yellow crystalline solid or liquid
Odor Mild aromatic or nitro odor
Boiling Point 215°C
Melting Point 22°C
Density 1.47 g/cm3
Solubility Insoluble in water; soluble in acetone, ether, benzene, etc
Viscosity Not determined
Flash Point 96°C

FAQs

1. What is the current price of 3,4-Difluoronitrobenzene in India?
The price of 3,4-Difluoronitrobenzene can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy 3,4-Difluoronitrobenzene in India?
You can purchase 3,4-Difluoronitrobenzene from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for 3,4-Difluoronitrobenzene? 
Our minimum order quantity (MOQ) for 3,4-Difluoronitrobenzene is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of 3,4-Difluoronitrobenzene supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.