2,4-Dinitrofluorobenzene

2,4-Dinitrofluorobenzene

1-Fluoro-2,4-dinitrobenzene; 1,3-Dinitro-4-fluorobenzene; DFB; DNFB

CAS 70-34-8

Chemical Formula C6H3FN2O4

Molecular Weight 186.10 g/mol

2,4-Dinitrofluorobenzene (DNFB) is a chemical compound used as a reagent in organic chemistry, particularly in protein sequencing and the study of amino acids. It reacts with the free amino group of N-terminal amino acids in peptides and proteins, forming a stable dinitrophenyl (DNP) derivative. This reaction is the basis of the Sanger method for N-terminal amino acid sequencing. 

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Industrial Uses

1. Performance Chemicals

  • Protein Sequencing: Sanger's reagent, also known as DNFB, is famously used to determine the N-terminal amino acid of a peptide or protein. It reacts with the free amino group of the N-terminal amino acid, forming a dinitrophenyl (DNP) derivative. After hydrolysis, the DNP-labeled amino acid can be identified, allowing for the determination of the protein's sequence. 
  • Derivatization of Amines: DNFB is used to derivatize primary amines, including the amino groups in amino acids, peptides, and proteins. This derivatization can be used to enhance the properties of the molecule for analysis or further reactions. 
  • Analytical Chemistry: DNFB is employed in chromatographic methods to separate and identify various compounds.  It can be used to detect and quantify amino acids and proteins, aiding in the analysis of complex mixtures.
  • Organic Synthesis: DNFB serves as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It can be used as a building block in the synthesis of more complex molecules.
  • Material science: DNFB is used in material science to create cross-linked polymer materials, improving their mechanical properties.

2. Agrochemicals

  • Pesticide Synthesis: DNFB is used to introduce specific chemical groups into pesticide molecules, potentially improving their effectiveness or altering their properties.

Specifications

Assay 98%
Appearance Pale yellow to yellow crystalline solid
Odor Slight, aromatic odor
Boiling Point 265°C
Melting Point 33°C
Density 1.65 g/cm3
Solubility Slightly soluble in water; soluble in ethanol, acetone, ether
Viscosity Not applicable
Flash Point 110°C

Hazard Symbols

Acute Toxicity
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of 2,4-Dinitrofluorobenzene in India?
The price of 2,4-Dinitrofluorobenzene can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.6301 00 6301 directly for a customized quote tailored to your needs.

2. Where can I buy 2,4-Dinitrofluorobenzene in India?
You can purchase 2,4-Dinitrofluorobenzene from MULTICHEM, a leading exporter with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across global markets. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for 2,4-Dinitrofluorobenzene? 
Our minimum order quantity (MOQ) for 2,4-Dinitrofluorobenzene is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of 2,4-Dinitrofluorobenzene supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.